Botox and neuromodulators · Upper East Side, New York

Botox and Other Neuromodulators in NYC

Rested, softer and still completely you.

A neuromodulator softens the frown and forehead lines that can make you look tired or upset on days you feel wonderful, while keeping the warmth of your smile. I use six, including Botox, and choose the one that fits you.

Who injects
Dr. Day, every time
Treats
Frown, forehead and crow's feet lines, neck bands
You'll notice
Within 2 to 4 days; full effect at about 2 to 3 weeks
Lasts
About 3 to 4 months
Downtime
Usually straight back to your day

What a neuromodulator can do for you

Every time you frown, a nerve sends a small message asking the muscle to contract. A neuromodulator quiets that message where the nerve meets the muscle, so the line above it folds less and can soften. The effect is temporary, and the muscle gradually returns to how it worked before.

Six to choose from

Botox Cosmetic, Dysport, Xeomin, Jeuveau, Daxxify and Letybo. I choose the one that fits you.

Just enough

A small amount, placed thoughtfully, relaxes one muscle and leaves the rest of your expression free.

One plan

Often paired with fillers for support and lasers for skin quality.

Botox, Dysport, Xeomin, Jeuveau, Daxxify and Letybo compared

All six are forms of botulinum toxin type A, but each is its own distinct medicine with its own unique properties, and their units can't be compared or converted from one brand to another. You don't need to arrive knowing which one you want. That part is my job.

In my practice, the timing tends to be similar across all six: effects typically begin within 2 to 4 days, reach full effect at about 2 to 3 weeks, and last about 3 to 4 months, sometimes longer with Daxxify.

Xeomin is a pure form of botulinum toxin type A, without additives, because certain proteins are removed during processing. That may lower the already very rare chance of your body developing antibodies to it, and people who want a softer look often love the freedom of movement it allows. Jeuveau is a purified 900 kDa botulinum toxin type A. It is precise and wonderful for targeting a specific area.

Movement is one part of the picture

A neuromodulator can soften lines that come from movement, but it doesn't restore structure or change the quality of your skin. A more natural look often comes from one plan for your whole face: a neuromodulator for movement, fillers, Sculptra or Radiesse for support, and laser treatments and daily skin care for the skin itself. My longevity dermatology page explains how I think about skin over a lifetime.

Is it right for you?

A neuromodulator suits lines that come from movement. The areas I treat most often:

Frown lines · Forehead lines · Crow's feet · Neck bands · Jaw and TMJ

If a line is still there when your face is at rest, I'll look at structure and skin quality too, because a neuromodulator alone may not be the whole answer, and I'll always tell you so.

What to expect

  1. I

    We look together

    We look at your face together, and you tell me your goals and the features you love. Mostly, I listen.

  2. II

    Your plan for the year

    I do a full assessment, studying your face at rest and while you talk. Then I walk you through your complete plan, from skin care and your at-home routine to in-office treatments, and map it into a calendar for the year so you can plan ahead and look forward to every visit. My assistant takes notes, reviews the plan with you and gives you a printed copy, plus one by email, before you leave.

  3. III

    Treatment, then follow-up

    I give every injection myself. To keep things smooth, avoid scheduling injections right before a dental cleaning or major dental work, or within two weeks of a vaccine. Afterward we stay in touch and follow your calendar together, helping you reach your goals and making every decade your most beautiful best.

Go easy for the rest of the day: don't rub or press on the treated areas, and skip facials and hard workouts until tomorrow. You'll leave with it all written down.

Results that look like you

What we're after is simple: you, rested and beautiful, with a face that still moves naturally. You'll typically see a softening within 2 to 4 days, and it keeps building gently to its full effect at about 2 to 3 weeks. Results usually last about 3 to 4 months, and often longer with Daxxify, so we plan your next visit around your own timing.

My goal is to help you age beautifully and in the healthiest way possible.

Doris Day, MD

Judgment you can see in the result

How well a neuromodulator works depends on the judgment behind it: the dose, the exact placement, and knowing when to hold back. I'm a master injector, injecting for over 25 years, and I lecture nationally and internationally for my peers on injection technique.

Training and research

I've been certified by the American Board of Dermatology since 1998 and supervise NYU dermatology residents at Bellevue Hospital, where I lead injection training sessions as a Clinical Professor of Dermatology at NYU Grossman School of Medicine. I co-authored international consensus recommendations on combining botulinum toxin, fillers and energy-based devices in the face, and I was on the team that designed the Wrinkle Severity Rating Scale. Castle Connolly inducted me into its Hall of Fame in 2023, and on both Newsweek lists I was ranked #3 among cosmetic dermatologists. Since 2008 I've hosted a dermatology show on Doctor Radio on SiriusXM.

Skin care that works alongside your injections

Because a neuromodulator doesn't change the quality of your skin, each patient also gets a home routine planned around the injections. On the day of your injections the routine stays simple, and no specific preparation is needed. Over the following months we focus on skin tone, texture and sun protection, and on restoring facial balance with lasers, devices and injectables.

Coming from out of town

Patients fly in from across the US and abroad for this treatment. It usually fits into a short trip, because it's typically a single appointment. For a wedding or a big event, plan to come in 1 to 2 weeks ahead so the result has time to settle. If you'd like filler or a laser treatment on the same trip, I'll tell you what can be done together. See traveling for treatment and finding the office. The Surrey, The Carlyle, The Mark and The Lowell are within about a 10-minute walk.

Your questions, answered

Who does the injections?

Me, every time. I give every injection myself.

What is Botox?

Botox is a purified protein injected in tiny amounts to relax specific facial muscles, softening the lines they etch over time. I love it because it's quick and subtle: a forehead that stays smooth when you laugh at dinner, and friends who say you look rested without guessing why. It is made from botulinum toxin type A, highly purified and measured in precise units.

What does Botox do, and how does it work?

Botox temporarily quiets the nerve signal that tells a muscle to contract, so the crease that muscle folds into the skin relaxes and softens. The result is smoother frown lines, forehead lines and crow's feet while your expressions stay your own, whatever your skin tone or type.

How long does Botox last?

For most people, about three to four months. After that, movement gradually returns and the lines slowly come back. With regular, well-planned treatments, results feel steady across the seasons. Metabolism, muscle strength and dose all play a role, so we tailor the timing to you.

How long does Botox take to kick in?

Most people notice it working within two to four days, and the full effect shows at about two to three weeks. I like to plan treatment at least three weeks before a big event, which is also when we check in and refine if needed.

How often should I get Botox?

Most people return every three to four months, when movement and lines start coming back. Some stretch it longer. We build a rhythm around your life, so the treatment fits your calendar rather than ruling it.

What is "baby Botox" or light dosing?

It means using smaller amounts, placed precisely, so lines soften while your face keeps more of its natural movement. It's a lovely choice for a first visit, for prevention, or for anyone who wants the most subtle, rested look. We can always build gradually from there.

How many units of Botox will I need?

It's individualized: it depends on the areas we treat, how strong your muscles are and the look you want. As a general frame, a single area such as the frown lines often takes around 20 units, and several areas together take more. At a first visit I tend to start conservatively and build from there.

How many units of Botox for the forehead?

Forehead lines typically take a modest dose, often around 10 to 20 units, but the right amount is individualized. I treat the forehead together with the frown muscles between the brows, which keeps the brow balanced and natural rather than heavy.

Does Botox hurt?

Only a few quick pinches from a very fine needle, and most people are surprised by how comfortable it is. The whole treatment takes minutes, and ice or a cooling touch makes it even easier.

What should I avoid after Botox?

For the rest of the day, skip strenuous workouts, facials, massages and rubbing the treated areas, and stay upright for about four hours. Everything else can resume right away. Most people head straight back to work or out to dinner.

How long after Botox can I lie down?

Stay upright for about four hours so the product settles where it was placed. Errands, desk work or lunch with a friend are all perfect, and bedtime that night is completely fine.

Which neuromodulators do you offer?

Six: Botox Cosmetic, Dysport, Xeomin, Jeuveau, Daxxify and Letybo. You don't have to choose. I'll pick the product and dose that you need.

Will I still look like myself?

That's my goal, every time. I study how your face moves and use only what you need, so you look rested, not "done". We can always add a little more later.

How do I choose a Botox injector in NYC?

Ask who will give your injections, how they decide your dose, and what they want your face to look like in a year. Here, it is me, every time. I study how your face moves at rest and in conversation before I plan a single injection.

Is Botox safe? What are the side effects?

In experienced hands and at cosmetic doses, Botox has a long, well-studied safety record. The most common side effects are mild and temporary, such as a small bruise, slight tenderness or a brief headache. I review your health history first and place every injection with care.

Can I have Botox and filler on the same day?

Often, yes. I plan both around your whole face, and if it makes more sense to space them out, I'll tell you.

Can Botox slim the jaw?

Yes, and it can help TMJ, but it needs to be done carefully and precisely to keep the best facial contour. Let's talk about whether it fits your face.

Medically reviewed by Doris Day, MD, FAAD · Last reviewed October 11, 2026

Let's plan your visit

In person or virtual. Take your time deciding.

Day Dermatology & Aesthetics · 10 East 70th Street, Suite 1C, New York, NY 10021 · Across from The Frick Collection

Monday 9:30 AM to 6 PM · Tuesday, Wednesday and Friday 9 AM to 5 PM · Thursday 9 AM to 4 PM