Clinical Research at Day Dermatology and Aesthetics

Innovation has always been at the heart of dermatology. Through clinical research, we help advance our understanding of skin health and contribute to the development of new treatments that may improve the lives of patients today and in the future.

At Day Dermatology & Aesthetics, we are proud to participate in clinical research studies that explore promising therapies for a variety of skin, hair, and aesthetic concerns. These studies allow us to remain at the forefront of dermatologic innovation while offering eligible patients access to emerging treatment options under the guidance of our experienced research team.

Every study is carefully reviewed and conducted according to strict safety and ethical standards. Participation is always voluntary, and our team is committed to ensuring that each participant feels informed, supported, and cared for throughout the process.

We invite you to explore our current research opportunities below. By participating in clinical research, you may not only gain access to cutting-edge treatments, but also play a meaningful role in advancing the future of dermatology.

If you have a specific question about ongoing clinical trials, please email caela@drdorisday.com.

Estrogen Study

This study is being done to see whether applying a cream with estradiol (a form of estrogen) to the face can improve overall skin quality and help reduce fine lines and wrinkles in peri- and post-menopausal women, and how this relates to epigenetic changes in the skin. A part of the study will also include applying an extra rapamycin analog cream to the face, which is also believed to improve overall skin quality and help reduce fine lines and wrinkles.

WHY THIS MATTERS

Skin aging in peri- and post-menopausal women is deeply tied to hormonal shifts. This study explores whether topical estradiol can turn back the clock – cellularly.

Eligibility

You MAY qualify if you can answer YES to all:

I am a healthy female (peri or menopausal) between the ages of 40 and 65.

I have not had any cosmetic facial treatments in the last 1-3 months.

I have not had any GLP-1 treatments in the last 6 months.

Study Design and Duration

The study includes daily evening application of study cream for 12 weeks, followed by 4 weeks with no test product use. In total, the study will last 16 weeks or approximately 4 months.

Apply to the Estrogen Study

Topical Scalp Serum Containing RLX‑201 in Subjects With Mild‑to‑Moderate Hair Thinning 

Purpose of the Study 

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of a scalp serum containing RLX‑201 when applied once daily for 20 weeks in men and women with mild‑to‑moderate hair thinning. The study will assess changes in hair density, hair thickness, and overall scalp health using clinical evaluations, imaging tools, and participant self‑assessments. 

Eligibility

You MAY qualify if you can answer YES to all:

I am a healthy male or female between the ages of 30 and 60.

Self‑perceived mild‑to‑moderate hair thinning.

I have NOT used minoxidil, light therapy, or other hair growth treatments within 3 months.

I have NOT used medications affecting hair growth (e.g., finasteride, spironolactone, cyproterone acetate, 5‑alpha‑reductase inhibitors) or a GLP-1 within 6 months.

Study Design and Duration 

This is a single‑center clinical study lasting approximately 20 weeks. If you agree to participate, you will be asked to attend study visits at the following time points: Baseline, and Weeks 2, 4, 8, 12, 16, and 20. 

Apply Here