This study is being done to see whether applying a cream with estradiol (a form of estrogen) to the face can improve overall skin quality and help reduce fine lines and wrinkles in peri- and post-menopausal women, and how this relates to epigenetic changes in the skin. A part of the study will also include applying an extra rapamycin analog cream to the face, which is also believed to improve overall skin quality and help reduce fine lines and wrinkles.

Click here to apply: Estrogen Study Screening